Scoring criteria for determining the safety of liver resection for malignant liver tumors

作     者：Kohei Harada Minoru Nagayama Yoshiya Ohashi Ayaka Chiba Kanako Numasawa Makoto Meguro Yasutoshi Kimura Hiroshi Yamaguchi Masahiro Kobayashi Koji Miyanishi Junji Kato Toru Mizuguchi 

作者机构：Departments of SurgerySurgical Scienceand OncologySapporo Medical UniversitySapporoHokkaido 060-8556Japan Division of RadiologySapporo Medical University HospitalSapporoHokkaido 060-8556Japan Sapporo Medical University Postgraduate School of Health Science and MedicineSapporo Medical UniversitySapporoHokkaido 060-8556Japan Research and Education Center for Clinical PharmacyKitasato University School of PharmacyTokyo 108-8641Japan Department of Internal Medicine IVSapporo Medical UniversitySapporoHokkaido 060-8556Japan Department of Nursing and Surgical ScienceSapporo Medical UniversitySapporo 0608543Japan 

出 版 物：《World Journal of Meta-Analysis》 (世界荟萃分析杂志)

年 卷 期：2019年第7卷第5期

页      面：234-248页

学科分类：10[医学] 

基　　金：Supported by a Grant-in-Aid for Scientific Research from the Ministry of Education,Culture,Sports,Science,and Technology,Japan,No.23591993 to TM,and No.24791437 to MM,No17K10672 to T Mizuguchi supported by Astellas Pharma,Inc.,No.RS2018A000763,Tokyo,Japan Daiichi Sankyo Company,No.1800461,Tokyo,Japan Shionogi&Co.,No.RS2018A000439931,Osaka,Japan Merk Serono,No.MSJS20180613001,Tokyo,Japan Sapporo Doto Hospital,No.30037656,Sapporo,Japan Noguchi Hospital,No.30047663,Otaru,Japan Doki-kai Tomakomai Hospital,No.30047674,Tomakomai,Japan Tsuchida Hospital,No.30057704,Sapporo,Japan Ikuta Hospital,No.30057704,Shiraoi,Japan was given to TM 

主　　题：Standard liver volume Residual liver volume Hepatectomy Mortality Liver failure Liver function 

摘      要：BACKGROUND Liver resection has become safer as it has become less ***,the minimum residual liver volume(RLV)required to maintain homeostasis is ***,the formulae used to calculate standard liver volume(SLV)are *** To review previously reported SLV formulae and the methods used to evaluate the minimum RLV,and explore the association between liver volume and *** A systematic review of Medline,PubMed,and grey literature was *** in the retrieved articles were cross-checked manually to obtain further *** last search was conducted on January 20,*** developed an SLV formula using data for 86 consecutive patients who underwent hepatectomy at our institution between July 2009 and August *** Linear regression analysis revealed the following formula:SLV(mL)=822.7×body surface area(BSA)?183.2(R2=0.419 and R=0.644,P0.001).We retrieved 25 studies relating to SLV formulae and 12 studies about the RLV required for safe liver *** the previously reported formulae included various coefficient and constant values,a simplified version of the SLV,the common SLV(cSLV),can be calculated as follows:cSLV(mL)=710 or 770×*** minimum RLV for normal and damaged livers ranged from 20%-40%and 30%-50%,*** Sapporo score indicated that the minimum RLV ranges from 35%-95%depending on liver *** We reviewed SLV formulae and the minimum RLV required for safe liver *** Sapporo score is the only liver function-based method for determining the minimum RLV.