Study progression in application of process analytical technologies on film coating

作     者：Tingting Peng Ying Huang Liling Mei Linna Wu Longkai Chen Xin Pan Chuanbin Wu 

作者机构：School of Pharmaceutical SciencesSun Yat-Sen UniversityGuangzhou 510006China Guangdong Research Center for Drug Delivery SystemsGuangzhou 510006China 

出 版 物：《Asian Journal of Pharmaceutical Sciences》 (亚洲药物制剂科学（英文）)

年 卷 期：2015年第10卷第3期

页      面：176-185页

核心收录：

学科分类：08[工学] 080502[工学-材料学] 0805[工学-材料科学与工程（可授工学、理学学位）] 

基　　金：supported by National Natural Science Foundation of China(81202476) Medical Research Foundation of Guangdong Province(B2012079) 

主　　题：Film coating Process analytical technologies (PAT) Spectroscopic techniques Imaging techniques 

摘      要：Film coating is an important unit operation to produce solid dosage forms,thereby,the monitoring of this process is helpful to find problems in time and improve the quality of coated *** methods adopted to monitor this process include measurement of coating weight gain,performance of disintegration and dissolution test,***,not only do these methods cause destruction to the samples,but also consume time and *** have recently emerged the applications of process analytical technologies(PAT)on film coating,especially some novel spectroscopic and imaging technologies,which have the potential to real-time track the progress in film coating and optimize production *** article gives an overview on the application of such technologies for film coating,with the goal to provide a reference for the further researches.