遗传性血色病与运动障碍无关
Hereditary haemochromatosis is unlikely to cause movement disorders: A critical review作者机构：Sobell Dept. Motor Neurosci. M. Institute of Neurology University College London Queen Square LondonWC1N 3BG United Kingdom
出 版 物：《世界核心医学期刊文摘（神经病学分册）》 (Digest of the World Core Medical Journals:Clinical Neurology)
年 卷 期：2005年第1卷第1期
页 面：12-13页
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题：遗传性血色病 运动障碍 肌张力障碍 舞蹈症 喉肌 颈肌 族性 进行性加重 因果关系
摘 要：Hereditary haemochromatosis (HH) is a common autosomal recessive systemic iron overload disorder in which CNS manifestations, particularly movement disorders, have been reported. We report a 63 year old woman with familial HH with a four year history of progressive gait disturbance, chorea, and mild cervical and laryngeal dystonia. Her movement disorder was thought to be related to the haemochromatosis. On further investigation, analysis for the Huntington’ s disease expansion was positive. A review of the seven published cases of movement disorders associated with HH as well as data concerning brain iron deposition in this condition leads us to debate the causal link between movement disorders and HH. We suggest that ovement disorders are rare in association with HH, and that such patients should be thoroughly investigated for another cause for their movement diorder.
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