Synthesis, Crystal Structure and Fungicidal Activity of 3-(Difluoromethyl)-1-methyl-N-((2-(trifluoromethyl)phenyl) carbamoyl)-1H-pyrazole-4-carboxamide

作     者：SUN Na-Bo ZHAI Zhi-Wen TONG Jian-Ying CAI Peng-Peng HE Fang-Yue HAN Liang LIU Xing-Hai 孙娜波;翟志文;童建颖;蔡彭鹏;何方岳;韩亮;刘幸海

作者机构：College of Biology and Environmental Engineering Zhejiang Shuren University Hangzhou 310015 China College of Chemical Engineering Zhejiang University of Technology Hangzhou 310014 China 

出 版 物：《Chinese Journal of Structural Chemistry》 (结构化学（英文）)

年 卷 期：2019年第38卷第5期

页      面：706-712,668页

核心收录：

学科分类：0817[工学-化学工程与技术] 08[工学] 

基　　金：funded by the Public Science&Technology Project of Zhejiang Province(No.2017C32011) Mid-Youth Academic Team of Zhejiang Shuren University Natural Science Foundation of Zhejiang Province(No.LY19C140002) 

主　　题：pyrazole acyl urea synthesis crystal structure fungicidal activities 

摘      要：The title compound 3-（difluoromethyl）-1-methyl-N-（（2-（trifluoromethyl）phenyl）-carbamoyl）-1 H-pyrazole-4-carboxamide(C14 H11 F5 N4 O2) was synthesized, and its structure was confirmed by 1 H NMR, H RMS and X-ray diffraction. It crystallizes in monoclinic system, space group P21/n with a = 6.994（3）, b = 13.860（6）, c = 15.308（7） ?, β = 97.632（6）°, V = 1470.8（11） ?3,Z = 4, the final R = 0.0692 and wR = 0.2108 for 3989 observed reflections with Ⅰ 2σ（Ⅰ）. The preliminary biological test shows that the title compound has moderate fungicidal activities against Pseudomonas syringae.