Applications of new irradiation modalities in patients with lymphoma:Promises and uncertainties

作     者：Youlia M Kirova Cyrus Chargari 

作者机构：Department of Radiation OncologyInstitut Curie 26rue d'Ulm75248 ParisCedex 05France 

出 版 物：《World Journal of Radiology》 (世界放射学杂志（英文版）（电子版）)

年 卷 期：2011年第3卷第3期

页      面：66-69页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Hodgkin lymphoma Helical tomotherapy Cardiac toxicity Secondary cancers 

摘      要：New highly conformal irradiation modalities have emerged for treatment of Hodgkin *** Tomotherapy offers both intensity-modulated irradiation and accurate patient positioning and was shown to significantly decrease radiation doses to the critical *** we review some of the most promising applications of helical tomotherapy in Hodgkin *** decreasing doses to the heart or the breast,helical tomotherapy might decrease the risk of long-term cardiac toxicity or secondary breast cancers,which are major concerns in patients receiving chest *** strategies,such as debulking radiotherapy prior to stem cell transplantation or total lymphoid irradiation may be clinically ***,helical tomotherapy may also increase the volume of tissues that receive lower doses,which has been implicated in the carcinogenesis *** assessments of these new irradiation modalities of helical tomotherapy are required to confirm the potential benefits of highly conformal therapies applied to hematological malignancies.