Study on the Interaction between Distamycin Analogs and DNA from Herring Sperm by Fluorimetry

作     者：Han LIANG Jing Jian LI Xiao Dong LI Fei Li TANG Gu YUAN 

作者机构：Department of ChemistryPeking UniversityBeijing 100871 The Key Laboratory of Bioorganic Chemistry and Molecular EngineeringDepartment of Chemical BiologyPeking UniversityBeijing 100871 

出 版 物：《Chinese Chemical Letters》 (中国化学快报(英文版))

年 卷 期：2002年第13卷第10期

页      面：1001-1002页

核心收录：

学科分类：0710[理学-生物学] 071010[理学-生物化学与分子生物学] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 

基　　金：The project was supported by the National Natural Science Foundation of China (No.39970169 29872001) 

主　　题：Distamycin analogs fluorescence quenching DNA from herring sperm. 

摘      要：The fluorescence spectra of the interaction between four new distamycin analogs and DNA from herring sperm have been studied in detail. The fluorescence quenching of the DNA by the analogs was observed, and the fluorescence intensity of the DNA was attenuated exponentially with the increasing of the analogs concentration.