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Dentinogenic ghost cell tumor: A case report

Dentinogenic ghost cell tumor: A case report

作     者:Sangeeta R Patankar Palak Khetan Sheetal K Choudhari Harshal Suryavanshi 

作者机构:Department of Oral Pathology and Microbiology Yerala Medical Trust’s Dental College and Hospital Department of Oral and Maxillofacial Surgery Yerala Medical Trust’s Dental College and Hospital 

出 版 物:《World Journal of Clinical Oncology》 (世界临床肿瘤学杂志(英文版))

年 卷 期:2019年第10卷第4期

页      面:192-200页

学科分类:1002[医学-临床医学] 10[医学] 

主  题:Dentinoid Ghost cells Calcifying odontogenic cyst Dentinogenic ghost cell tumor Case report Van Gieson 

摘      要:BACKGROUND Dentinogenic ghost cell tumor(DGCT) is an uncommon locally invasive odontogenic neoplasm. It is considered to be a solid variant of calcifying odontogenic cyst(COC). This tumor makes up for only 2%-14% of all COCs and less than 0.5% of all odontogenic tumors which owes to its rarity. The purpose of this paper was to describe a case of DGCT and the treatment adopted in our case,and to provide a review of this case in the indexed *** SUMMARY In this article, we discussed a case of 18 year old male who reported with a chief complaint of a recurrent swelling and dull aching pain in upper left back region of the jaw. Computed tomography scan was carried out which revealed hypodense lesion with a few hyperdense flecks within it suggesting the presence of calcification. On incisional biopsy, diagnosis of COC was given. After segmental resection of the lesion, histopathogically odontogenic epithelium was noted along with calcifications, ghost cells and dentinoid material. Special staining was done with van Gieson and it showed pink areas of dentinoid material and yellow colour represented ghost cells. Hence, amalgamation of careful clinical examination, use of advanced radiographic imaging and detailed histopathological examination confirmed the diagnosis of DGCT. The patient was followed up for one year and there was no recurrence of the lesion or signs of any residual *** Radical treatment should be carried out along with mandatory long-term follow up in order to avoid recurrence in aggressive lesions.

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