Estimation of Probability of Unprotected Heterosexual Vaginal Transmission of HIV-1 from Clients to Female Sex Workers in Kaiyuan,Yunnan Province, China

作     者：WEN-JUAN MA JUN-JIE WANG KATHLEEN-H. REILLY AI-MEI BI GUO-WEI DING KUMI SMITH NING WANG 

作者机构：School of Public Health Peking Union Medical College Tsinghua University Beijing 100730 China National Center for AIDS/STD Control and Prevention Beijing 102206 China Tulane University Health Sciences Center School of Public Health and Tropical Medicine New Orleans LA USA Kaiyuan Center for Disease Control and Prevention Kaiyuan 661600 Yunnan China University of North Carolina at Chapel Hill Chapel Hill NC USA 

出 版 物：《Biomedical and Environmental Sciences》 (生物医学与环境科学（英文版）)

年 卷 期：2010年第23卷第4期

页      面：287-292页

核心收录：

学科分类：090603[农学-临床兽医学] 12[管理学] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1201[管理学-管理科学与工程(可授管理学、工学学位)] 1001[医学-基础医学(可授医学、理学学位)] 09[农学] 0906[农学-兽医学] 

基　　金：supported by the mega-projects of national science research for the 11th Five-Year Plan of China (2008ZX10001-003) 

主　　题：Transmission Probability HIV/AIDS Model FSW Clients 

摘      要：Objective To estimate the probability of unprotected heterosexual vaginal transmission of HIV-1 from clients to Female Sex Workers （FSWs） in Kaiyuan County, Yunnan province, China, and analyze factors which impact the transmission probability. Methods An open cohort research of FSWs in Kaiyuan was created from surveys conducted in April 2008, October 2008, and April 2009. Two cross-sectional surveys of local clients were also carried out in May 2008 and November 2008. A model was developed to estimate the probability of unprotected heterosexual vaginal transmission of HIV-1 from clients to FSWs. Results The transmission probability from clients to FSWs was estimated as 0.0023 [95% CI 0.0014-0.0032] per unprotected heterosexual act. Conclusion The transmission probability among this group engaging in commercial sex in Yunnan province differs from that found in studies from other countries, and future studies should estimate the influence factors of HIV-1 transmission probability, such as stage of HIV infection, co-morbid sexually transmitted infections （STIs）.