Relationship between retinopathy and cirrhosis

作     者：Colakoglu Onder Taskiran Bengur Dayi Selcuk Sozmen Bulent Unsal Belkis Maden Ahmet Pasa Eser Aslan S. Leyla 

作者机构：Clinics of Gastroenterology Izmir Ataturk Teaching and Research HospitalIzmirTurkey 3rd Clinics of Internal Medicine Izmir Ataturk Teaching and Research Hospital IzmirTurkey Clinics of Ophthalmology Izmir Ataturk Teaching and Research HospitalIzmirTurkey 3rd Clinics of Internal Medicine Izmir Ataturk Teaching and Research HospitalIzmirTurkey Clinics of Ophthalmology 9th September University HospitalIzmirTurkey 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2005年第11卷第14期

页      面：2193-2196页

核心收录：

学科分类：1002[医学-临床医学] 100212[医学-眼科学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Cirrhosis Portal hypertension Retinopathy 

摘      要：AIM: To evaluate ophthalmic disorders with special attention to retinopathy in cirrhotic patients. Vitamin A deficiency-related ophthalmopathy, xerophthalmia, and color blindness may be documented in cirrhosis due to various etiologies. Retinopathy is an obscure feature of cirrhosis. METHODS: Thirty-two cirrhotic patients, who were followed up by Clinics of Gastroenterology, Izmir Ataturk Teaching and Research Hospital, were enrolled to the study. Associated systemic diseases such as diabetes mellitus and hypertension were excluded. Thirty-two healthy volunteers took part as the control subjects. All participants had ophthalmologic examination in the same hospital. RESULTS: Five (15.6%) of the cirrhotic subjects had soft exudate in the retina. None of the control subjects had retinopathy (P0.05). Intraocular pressure (IOP) measured for both eyes were also significantly lower in the cirrhotics (P0.05 vs P = 0.01). There were no statistically significant differences between the two groups in terms of other ophthalmic pathologies. The ophthalmic findings did not show up any differences according to the etiology of cirrhosis. CONCLUSION: Soft exudates may develop in cirrhotic patients probably due to loss of synthetic function of liver and hemodynamic effects of portal hypertension. Retinopathy must be sought in cirrhosis because of its severe morbidity.