3T相控阵MRI改善局灶性癫痫的术前评估:一项前瞻性研究

作     者：Knake S. Triantafyllou C. Wald L.L. P.E.Grant 赵天智 

作者机构：Pediatric Neuroradiology Department of RadiologyNeuro-radiology Section 55Fruit Street Boston MA 02114-2696 United States.Dr 

出 版 物：《世界核心医学期刊文摘(神经病学分册)》 (Digest of the World Core Medical Journals.Clinical Neurology)

年 卷 期：2006年第2期

页      面：46-47页

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

主　　题：癫痫 MRI 脑病 局灶性 术前评估 相控阵 声纳基阵 

摘      要：Background: Although detection of concordant lesions on MRI significantly improves postsurgical outcomes in focal epilepsy (FE), many conventional MR studies remain negative. The authors evaluated the role of phased array surface coil stu dies performed at 3 Tesla (3T PA MRI). Methods: Forty patients with medically in tractable focal epilepsies were prospectively imaged with 3T PA-MRI including h igh matrix TSE T2, fluid attenuated inversion recovery, and magnetization prepar ed rapid gradient echo. All patients were considered candidates for epilepsy sur gery. 3T PA-MRIs were reviewed by a neuroradiologist experienced in epilepsy im aging with access to clinical information. Findings were compared to reports of prior standard 1.5T MRI epilepsy studies performed at tertiary care centers. Res ults: Experienced, unblinded review of 3T PA-MRI studies yielded additional dia gnostic information in 48%(19/40) compared to routine clinical reads at 1.5T. I n 37.5%(15/40), this additional information motivated a change in clinical mana gement. In the subgroup of patients with prior 1.5T MRIs interpreted as normal, 3T PA-MRI resulted in the detection of a new lesion in 65%(15/23). In the subg roup of 15 patients with known lesions, 3T PA-MRI better defined the lesion in 33%(5/15). Conclusion: Phased array surface coil studies performed at 3 Tesla r ead by an experienced unblinded neuroradiologist can improve the presurgical eva luation of patients with focal epilepsy when compared to routine clinical 1.5T s tudies read at tertiary care centers.