In vitro antimicrobial activity of mangrove plant Sonneratia alba

作     者：Shahbudin Saad Muhammad Taher Deny Susanti Haitham Qaralleh Anis Fadhlina Izyani Bt Awang 

作者机构：Institute of Oceanography and Maritime Studies Kulliyyah of Science International Islamic University MalaysiaJalan Sultan Ahmad ShahBandar Indera Mahkota25200 Kuantan Pahang Malaysia Department of Pharmaceutical Technology Faculty of Pharmacy International Islamic University MalaysiaJalan Sultan Ahmad Shah25200Kuantan Pahang Malaysia Department of Biomedical Science Faculty of Science International Islamic University MalaysiaJalan Sultan Ahmad Shah25200 KuantanPahang Malaysia 

出 版 物：《Asian Pacific Journal of Tropical Biomedicine》 (亚太热带生物医学杂志（英文版）)

年 卷 期：2012年第2卷第6期

页      面：427-429页

学科分类：0710[理学-生物学] 0831[工学-生物医学工程（可授工学、理学、医学学位）] 1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 100706[医学-药理学] 100602[医学-中西医结合临床] 10[医学] 

基　　金：financially supported by Faculty of Science International Islamic University Malaysia 

主　　题：Antibacterial Antifungal Sonneratia alba Mangroves Antimicrobial activity 

摘      要：Objective:To investigate the antimicrobial property of mangrove plantSonneratia alba(S. alba).Methods:The antimicrobial activity was evaluated using disc diffusion and microdilution methods against six microorganisms. Soxhlet apparatus was used for extraction with a series of solvents,n-hexane, ethyl acetate and methanol in sequence of increasing ***:Methanol extract appeared to be the most effective extract whilen-hexane extract showed no activity. The antimicrobial activities were observed against the gram positive bacteria Staphylococcus aureus(S. aureus) and Bacillus cereus(B. cereus), the gram negative Escherichia coli(E. coli) and the yeast Cryptococcus neoformans. Pseudomonas aeruginosa and Candida albicans appeared to be not sensitive to the concentrations tested since no inhibition zone was observed.E. coli(17.5 mm) appeared to be the most sensitive strain followed by S. aureus(12.5 mm)and B. cereus(12.5 mm).Conclusions:From this study, it can be concluded that S. alba exhibit santim icrobial activities against certain microorganisms.