Bilateral gangrene of fingers in a patient on empagliflozin: First case report
Bilateral gangrene of fingers in a patient on empagliflozin: First case report作者机构：Endocrinology and Metabolism and Internal Medicine San Francisco VA Medical Center Santa Rosa CA 95492 United States Infectious Diseases and Internal Medicine San Francisco VA Medical Center Santa Rosa CA 95492 United States
出 版 物：《World Journal of Diabetes》 (世界糖尿病杂志（英文版）（电子版）)
年 卷 期：2019年第10卷第2期
页 面：133-136页
核心收录：
主 题：Empagliflozin Finger gangrene Non-healing ulcer Type 2 diabetes mellitus Sodium glucose cotransporter 2 inhibitor Jardiance Case report
摘 要：BACKGROUND Sodium glucose cotransporter 2(SGLT2)inhibitors use has been associated with toe amputations and non-healing ulcers and gangrene mostly of lower *** are no case reports about association of Empagliflozin with finger ulcers or *** is the first case report of Empagliflozin(Jardiance)an SGLT2 inhibitor causing gangrene of fingers and second case in literature about any SGLT2 inhibitor causing gangrene of upper *** SUMMARY A 76-year-old man with type 2 diabetes mellitus sustained minimal trauma to both middle fingers,which started *** was started on empagliflozin a week later for management of type 2 diabetes mellitus and started developing gangrene to both middle finger tips along with neuropathic pain which worsened over the course of next four *** were negative for vascular insufficiency,infection and vasculitis and imaging of hand was *** of empagliflozin slowed progression of gangrene and caused symptomatic improvement with reduction in neuropathic *** This case report suggests possible association of empagliflozin and finger gangrene and recommends that more research and awareness among clinicians is needed in this area.
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