Synthesis of substituted pyrazolo[1,5-α]pyrimidines

作     者：DEEB A.EL-MOBAYED M.ESSAWY A.ABDEL-HAMID A.ABDEL-HAMID ATEFM. 

作者机构：Chemistry Department Faculty of Science Zaguazig University Zagazig Egypt Chemistry Department Faculty of Science Zaguazig University Zagazig Egypt 

出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)

年 卷 期：1991年第9卷第5期

页      面：474-480页

核心收录：

学科分类：07[理学] 0703[理学-化学] 

主　　题：Pr DMSO 亚砜 Synthesis of substituted pyrazolo[1,5 pyrimidines 

摘      要：Condensation of 3-amino-4-cyanopyrazole (1) with ethylacetoacetate, ethyl cyanoacetate, diethyl malonate and acetylacetone afforded pyrazolo[1,5-a]pyrimidine derivatives (2-8a). Other compounds (8b-h) of this ring system were obtained by treatment of 1 with arylidenemalononitrile and ethylarylidenecyanoacetate. And the reaction of compound (1) with activated acetylenes yeilded pyrazolo[1,5-a]pyrimidine derivatives (11a-b).