足月儿和早产儿的颈总动脉血流:重复性及其与心排量的关系
Blood flow in the common carotid artery in term and preterm infants: Reproducibility and relation to cardiac output作者机构：Neonatal Unit Garden House Royal London HospitalWhitechapel London E1 1BB United Kingdom.Dr
出 版 物：《世界核心医学期刊文摘（儿科学分册）》 (Dkgest of the World Latest Medical Information)
年 卷 期：2006年第2卷第5期
页 面：14-15页
学科分类：1002[医学-临床医学] 100202[医学-儿科学] 10[医学]
主 题：可重复性 早产儿 足月儿 动脉血流 心排量 多普勒技术 平均血流速度 重复性研究 颈总动脉 超声测量
摘 要：Aim: To assess the reproducibility of, and determine normative data for, flow volume measurements from the right common carotid artery (CCA) and its relation to left ventricular output (LVO) in stable term and preterm babies using Doppler ultrasound. Methods: Right CCA flow volume was measured using a near focus, hig h frequency transducer by obtaining intensity weighted mean velocity and right C CA diameter. LVO was determined using standard Doppler techniques. Reproducibili ty studies were performed on 30 newborn infants by two observers. Normative data were obtained from 40 spontaneously bre athing preterm babies and 21 term babies. Results: The intraobserver coefficient of variation for CCA flow measurements was 10.5%for observer 1 and 15.4%for o bserver 2, whereas the interobserver coefficient of variation was 16.4%. In ter m and preterm infants, right CCA flow was about 20 ml/kg/min, accounting for 11 %of cardiac output. Among the preterm infants, there was a positive correlation of right CCA flow with gestation (r = 0.61, p 0.001), weight (r = 0.64, p 0 .001), and LVO (r = 0.59, p 0.001). Right CCA diameter also increased with wei ght (r = 0.63, p 0.001) and gestation (r = 0.58, p 0.001). The proportion of LVO distributed to the right CCA did not increase with gestation, nor did the r ight CCA flow per kg body weight. Conclusions: It is possible to perform reprodu cible measurements of flow volume in the CCA of newborn infants. In stable, spon taneously breathing babies, both cardiac output and carotid flow increased with gestation and body weight. The proportion of cardiac output distributed to the r ight CCA remained relatively constant across gestation.
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