Outcomes of men aged≤50 years treated with radical prostatectomy:a retrospective analysis

作     者：Byeongdo Song Hakmin Lee Min Seung Lee Sung Kyu Hong 

作者机构：Department of UrologySeoul National University Bundang HospitalSeongnam 13620Korea Department of UrologySeoul National University College of MedicineSeoul 03080Korea 

出 版 物：《Asian Journal of Andrology》 (亚洲男性学杂志（英文版）)

年 卷 期：2019年第21卷第2期

页      面：150-155页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：age group prostate cancer prostatectomy 

摘      要：Previous studies inv estigating prostate can cer(PCa)features in youn ger men have reported con flicting fin *** study aimed to investigate pathologic outcomes and biochemical recurrenee(BCR)status in younger men who underwent radical prostatectomy(RP)for *** of 2057 patients who underwent RP at Seoul National University Bundang Hospital(Seongnam,Korea)between 2006 and 2015 were reviewed;patients were divided according to age into the younger and older groups(men aged50 years,respectively).Postoperative BCR status and functional outcomes and clinicopathologic features were compared betwee n both *** an alyses were repeated after propensity score matchi *** men were more likely to have lowrisk disease(P0.001),lower pathologic Gleason score(P0.001)and pathologic stages(P0.001)than older *** pathologic Gleason score(P=0.002)and rates of extracapsular extension(P=0.004)were lower in younger men after propensity score *** multivariate analysis,age at RP was not an independent predictor of BCR-free survival after RP(P=0.669).Moreover,at 1 year after RP,younger men with preoperative 5?item International Index of Erectile Function score≥22(n=228)showed more favorable results for urinary con tine nee(defi ned as nonuse of pads daily)(99.4%vs 95%,P=0.009)and erections sufficie nt for vaginal in tercourse(81.8%vs 55.5%,P=0.001).Youn ger men had more favorable clinicopathologic features at RP than their older *** age was not an independent predictor of BCR status outcome,younger men had better functional outcomes following RP.