Clinical efficacy and safety of Traditional Chinese Medicine combined with Western Medicine in patients with diabetic acute ischemic stroke

作     者：Huan Zhao Dongdong Yang Min Shi Jingtao Liang XuhongYang Shuoguo Jin 

作者机构：Clinical Medical CollegeChengdu Traditional Chinese Medicine University Medical Department of NeurologyHospital Affiliated to Chengdu Traditional Chinese Medicine University 

出 版 物：《Journal of Traditional Chinese Medicine》 (中医杂志（英文版）)

年 卷 期：2014年第34卷第2期

页      面：145-149页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 1005[医学-中医学] 1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

基　　金：Supported by Sichuan Provincial Fund forTraining Academic Foregoers (No.JDZX2012133) 

主　　题：中国传统医学 中西医结合 临床疗效 糖尿病 脑卒中 安全性 治疗 缺血 

摘      要：OBJECTIVE: To observe the clinical efficacy and safety of Traditional Chinese Medicine(TCM) combined with Western Medicine(WM) in patients with diabetic acute ischemic stroke.METHODS: Ninety patients with diabetic acute ischemic stroke were randomly divided into a treatment group and a control group. The 45 patients in the treatment group were given standardized treatment with TCM combined with WM. They received corresponding oral Chinese decoctions three times daily, according to their TCM syndromes, along with basic western medical treatment. The 45 patients in the control group were given non-standardized treatment with TCM combined with WM.They received an oral Chinese decoction for promotion of blood circulation to inhibit hemostasis, re-gardless of their TCM syndromes, along with basic western medical treatment. The treatments lasted for 4 weeks. Scores were evaluated on the National Institutes of Health Stroke Scale(NIHSS)score, activity of daily life(ADL) scores, and TCM symptoms before treatment and 2 and 4 weeks after treatment.RESULTS: Analysis of variance for repeated measurements showed that there were significant differences in NIHSS and ADL score before and after treatment in both groups(P0.05).CONCLUSION: Standardized treatment was superior to non-standardized treatment for clinical efficacy of TCM combined with WM in patients with diabetic acute ischemic stroke, and the superiority was more obvious in improving neural dysfunction, ADL score, and TCM symptoms. The adverse reactions were similar in the two treatment groups.