巴多林腺Merkel细胞癌
Merkel cell carcinoma of the Bartholin' s gland作者机构:Department of Obstetrics and Gynecology State University of New York Downstate Medical Center 450 Clarkson Avenue Brooklyn NY 11203 United States
出 版 物:《世界核心医学期刊文摘(妇产科学分册)》 (Core Journal in Obstetrics/Gynecology)
年 卷 期:2005年第1卷第12期
页 面:42-42页
学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题:巴多林腺 Merkel细胞 燕麦细胞 神经内分泌癌 肿瘤起源 淋巴结清扫术 局部切除 临床行为 免疫组织化学 腹股沟区
摘 要:Background. There are a few cases of “ small cell neuroendocrine carcinoma of the Bartholin’ s gland as well as Merkel cell carcinoma of the vulva reported in the gynecologic oncology literature, most with aggressive clinical behavior. Merkel cells were originally described in the epidermis with neuroendocrine properties. Merkel cell carcinoma is different from the neuroendocrine small cell (oat cell) tumor arising in the lung and other internal organs based on morphology and immunohistochemistry. Case. A 49- year- old female was diagnosed with a FIGO stage I Merkel cell carcinoma of the Bartholin’ s gland. The tumor originated from the duct and stained with endocrine markers and cytokeratin 7 and 20. She was treated with radical wide local excision and bilateral inguinal lymph node dissection followed by radiation therapy to the pelvis, perineum, vulva, and inguinal regions. Two years after the diagnosis, she is alive with no evidence of recurrent disease. Conclusion. This is a case of Merkel cell carcinoma of the Bartholin’ s gland discovered in the early stage with a survival of 2 years following diagnosis and treatment with no evidence of disease recurrence.