Vitamin D:A new player in non-alcoholic fatty liver disease?

作     者：Myrto Eliades Elias Spyrou 

作者机构：Division of Endocrinology Diabetes and Nu-trition University of Maryland School of Medicine Department of Internal Medicine Medstar Washington Hospital Center 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2015年第21卷第6期

页      面：1718-1727页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Steatohepatitis Non-alcoholic fatty liver disease 

摘      要：Vitamin D through its active form 1a-25-dihydroxyvtamin D[1,25(OH)2D]is a secosteroid hormone that plays a key role in mineral *** years have witnessed a significant scientific interest on vitamin D and expanded its actions to include immune modulation,cell differentiation and proliferation and inflammation *** our understanding of the many functions of vitamin D has grown,the presence of vitamin D deficiency has become one of the most prevalent micronutrient deficiencies ***,non-alcoholic fatty liver disease(NAFLD)has become the most common form of chronic liver disease in western *** and vitamin D deficiency often coexist and epidemiologic evidence has shown that both of these conditions share several cardiometabolic risk *** this article we provide an overview of the epidemiology and pathophysiology linking NAFLD and vitamin D deficiency,as well as the available evidence on the clinical utility of vitamin D supplementation in NAFLD.