The application of immunoassay in bioanalysis
免疫分析方法在体内药物分析中的应用(英文)作者机构:湖南师范大学医学院湖南长沙410006 中南大学药学院湖南长沙410013
出 版 物:《Journal of Chinese Pharmaceutical Sciences》 (中国药学(英文版))
年 卷 期:2015年第24卷第4期
页 面:205-216页
核心收录:
学科分类:1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 100706[医学-药理学] 100602[医学-中西医结合临床] 10[医学]
基 金:National Natural Science Foundation of China(Gr ant No.81102499) Hunan Science and Technology Project(Grant No.2011SK3261)
主 题:Immunoassay Sample pretreatment Biological samples Bioanalysis
摘 要:Immunoassay technology is an analytical method with high sensitivity and specificity; it provides a technique to assay materials which cannot be measured by other methods, or are difficult to detect. It plays a very important role in biological sample pre-treatment, therapeutic drug monitoring and drug determination, and is one of the important means for in vivo drug analyses. This paper reviews immunoassays commonly used in bioanalysis, including immunoextraction and immunodepletion for pretreatment of biological samples, conventional immunoassay methods and new immunoassay technologies for determination of target drugs.