丙型肝炎和心脏:二者是否有关?

作     者：Kcomt W. Nahavandi A.A. Myaing M 梁磊 

作者机构：Internal Medicine St. Ba rnabas Hospital Affil. Weil Med. Coll. Cornell Univ. Bronx NY United States 

出 版 物：《世界核心医学期刊文摘（心脏病学分册）》 (Digest of the World Core Medical Journals(Cardiology))

年 卷 期：2005年第1卷第1期

页      面：26-26页

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

主　　题：丙型肝炎 丙肝患者 肥厚型心肌病 超声结果 队列分析 收缩功能障碍 扩张型心肌病 门脉高压 左室肥厚 病毒感染 

摘      要：Background: Many enteroviruses as well as hepatitis C have been increas ingly f ound in association with cardiomyopathies, even though, the evidence has been in conclusive. Methods: From 1998 to 2001, at the liver clinic of our community bas ed hospital, in the cohort of hepatitis C patients, infection evidence by PCR co nfirmation and echocardiographic measures of left ventricular (LV) function were obtained. Results: One hundred-eight patients were identified. Fifty percent o f them have echocardiographic abnormalities. Patients mean age was 55±10 year s; 45%women, 55%men; 32%had LVH, 13.8%had high right ventricular systolic pr essures, and 4%displayed contractility abnormalities. No cases of dilated or hy pertrophic cardiomiopathies were found. Conclusions: Echocardiographic abnormali ties are not uncommon findings associated with hepatitis C infection, however al l these findings can easily be explained by existing co-morbidities. High right ventricular systolic pressure, suggestive of pulmonary hypertension, which may be secondary to portal hypertension, is an independent finding for hepatitis C.