Effects of creep feeding and supplemental glutamine or glutamine plus glutamate (Aminogut) on pre- and post-weaning growth performance and intestinal health of piglets

作     者：Rafael A Cabrera James L Usry Consuelo Arrellano Eduardo T Nogueira Marianne Kutschenko Adam J Moeser Jack Odle 

作者机构：Laboratory of Developmental Nutrition Department of Animal ScienceNorth Carolina State University 101 Polk Hall North Carolina State UniversityRaleigh NC 27695 USA Huvepharma USA 525 West Park Drive Suite 230 Peachtree City GA 30269 USA Ajinomoto Heartland Lysine Department of Statistics North Carolina State UniversityRaleigh NC 27695-8203 USA Ajinomoto do Brasil. Ajinomoto Animal NutritionSāo Paulo SP 04015-001 Brazil Department of Population Health and Pathobiology College of Veterinary Medicine North Carolina State UniversityRaleigh NC 27695 USA Laboratory of Developmental Nutrition Department of Animal ScienceNorth Carolina State University 101 Polk Hall North Carolina State UniversityRaleigh NC 27695 USA 

出 版 物：《Journal of Animal Science and Biotechnology》 (畜牧与生物技术杂志（英文版）)

年 卷 期：2013年第4卷第3期

页      面：211-222页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 090502[农学-动物营养与饲料科学] 100705[医学-微生物与生化药学] 0905[农学-畜牧学] 09[农学] 10[医学] 

基　　金：Ajinomoto Heartland Lysine Ajinomoto do Brazil 

主　　题：Creep feeding Glutamine Growth performance Intestinal health SEM Villi 

摘      要：Background： Creep feeding is used to stimulate piglet post-weaning feed consumption.L-Glutamine（GLN） is an important source of fuel for intestinal epithelial *** objective of this study was to determine the impact of creep feeding and adding GLN or AminoGut（AG;containing glutamine ＋ glutamate） to pre-and post-weaning diets on pig performance and intestinal ***（N = 120） were allotted to four treatments during 14–21 d of lactation： 1） No creep feed（NC,n = 45）;2） creep fed control diet（CFCD,n = 45）;3） creep fed 1% GLN（CFGLN,n = 15）;4） creep fed.88% AG（CFAG,n = 15）.After weaning,the NC and CFCD groups were sub-divided into three groups（n = 15 each）,receiving either a control nursery diet（NC-CD,CFCD-CD） or a diet supplemented with either GLN（NC-GLN,CFCD-GLN） or with AG（NC-AG,CFCD-AG）.Litters that were creep fed with diets containing GLN or AG also were supplemented with those amino acids in the nursery diets（CFGLN-GLN,CFAG-AG）.Glutamine was added at 1% in all three post-weaning diet phases and AG was added at.88% in phase 1 and 2 and at.66% in phase ***： Feed conversion（feed/gain） showed means among treatment means close to significance（P = 0.056） and Tukey＇s test for pairwise mean comparisons showed that Pigs in the CFGLN-GLN group had the best feed conversion（feed/gain） in the first three-week period post-weaning,exceeding（P = 0.044） controls（CFCD-CD） by 34%.The NC-AG group had（P = 0.02） the greatest feed intake in the last three week of the study,exceeding controls（CFCD-CD） by 12%.CFGLN-GLN,CFCD-GLN and sow reared（SR） pigs had the greatest（P = 0.049） villi height exceeding the CFCD-AG group by 18%,20% and 19% *** CFAG-AG group had the deepest（P = 0.001） crypts among all ***-GLN,CFCD-GLN and SR groups had the greatest（P = 0.001） number of cells proliferating（PCNA） exceeding those in the NC-CD group by 43%,54% and 63% *** reared pigs showed the greatest（P = 0.001） intestinal absorption capacity for xylose and