The anti-obesity effects of EGCG in relation to oxidative stress and air-pollution in China

作     者：Simon CICHELLO Pingsheng LIU Markendya JOIS 

作者机构：School of Life SciencesLa Trobe UniversityVictoria 3086Australia National Laboratory of BiomacromoleculesInstitute of BiophysicsChinese Academy of SciencesBeijing 100101China Ministry of Education Key Laboratory of Pu'er TeaYunnan Agricultural UniversityYunnan 650201China 

出 版 物：《Natural Products and Bioprospecting》 (应用天然产物（英文）)

年 卷 期：2013年第3卷第6期

页      面：256-266页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：EGCG obesity air-pollution diesel exhaust fumes(DEF) 2PM reactive oxygen species(ROS) inflammation 

摘      要：Modern China,similar to most developing nations,has seen a rise in the prevalence of both obesity and diesel exhaust based air *** cause of obesity is multi-factorial encompassing diet,lifestyle and social *** there has been a reduction in the consumption of fruit,vegetables,and traditional medicinal foods such as polyphenol containing green *** these,are high fat and carbohydrate based processed foods which are quickly displacing these wholefoods in the *** review paper proposes evidence that a potential cause of obesity is also linked to environmental stress stimuli such as air pollutants,particularly diesel exhaust fumes(DEF)of2.5μm particulate matter,and discusses a role for a green tea catechin(EGCG)for use as a dietary defence against diet and environmentally induced *** is now at a critical point of a public health pandemic with rising air-borne pollution(via car exhaust fumes DEF),industry pollution such as heavy metals,and the benzene hydrocarbon based‘2PM’particulate matter,now accepted as a major environmental issue for public *** data published in MEDLINE since 1995 has been gathered to formulate the following review.