Outbreak of Salmonella Typhi enteric fever in sub-urban area of North India:A public health perspective

作     者：Nidhi Singla Neha Bansal Varsha Gupta Jagdish Chander 

作者机构：Department of MicrobiologyGovernment Medical College HospitalChandigarh160030India 

出 版 物：《Asian Pacific Journal of Tropical Medicine》 (亚太热带医药杂志（英文版）)

年 卷 期：2013年第6卷第2期

页      面：167-168页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 100705[医学-微生物与生化药学] 1001[医学-基础医学(可授医学、理学学位)] 100103[医学-病原生物学] 10[医学] 

主　　题：Enteric fever Fluoroquinolones Outbreak Salmonella 

摘      要：Outbreaks of enteric fever are a major health concern not only due to significant human morbidity and mortality but also fear of spread of multidrug resistant *** report an outbreak of enteric fever caused by Salmonella enterica serotype Typhi in a suburban area,in city Chandigarh of North ***-seven strains of *** were isolated from blood cultures over a period of two weeks with 18 of these 27 patients residing in the same *** cases were in the age group 5-14 years(10 patients,55.5%) while 4(22.2%) cases were children under 5 *** the strains showed similar resistogram being resistant to ampicillin and nalidixic acid,intermediate to ciprofloxacin and sensitive to chloramphenicol,ceftriaxone,cefotaxime,cotrimoxazole and azithromycin on disc diffusion *** inhibitory concentration of ciprofloxacin was determined by agar dilution method and was found to be raised(≥2μg/mL).This nalidixic acid resistant *** outbreak report warrants the necessity of implementing stringent sanitation practices in public health interest.