Studies on Different Hydrolysis Procedures for Drugs of Abuse in Hair
Studies on Different Hydrolysis Procedures for Drugs of Abuse in Hair作者机构：Chinese Acad Med Sci Inst Mat Med Beijing 100050 Peoples R China Peking Union Med Coll Beijing 100050 Peoples R China
出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)
年 卷 期：1999年第10卷第3期
页 面：239-242页
核心收录：
主 题：drugs of abuse hydrolysis hair
摘 要：Different hydrolysis and extraction procedures have been studied for the determination of drugs of abuse in hair samples. The results showed that acid and enzymatic hydrolysis gave high extraction recoveries for 6-monoacetylmorphine, morphine, codeine and heroin. Enzymatic hydrolysis was more expensive. After alkaline hydrolysis, 6-monoacetylmorphine, a unique proof of heroin abuse, could not be detected and after methanolic extraction, the extract was dirty and the obtained chromatogram showed an interfering background. It is concluded that acid hydrolysis is the extraction method of choice.
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