Sporadic Creutzfeldt-Jakob Disease Presenting with Visual Disturbance—A Case Report in China
Sporadic Creutzfeldt-Jakob Disease Presenting with Visual Disturbance—A Case Report in China作者机构:Department of Neurology Beijing Tongren Hospital Capital Medical University Beijing China. Department of Ophthalmology Eye and ENT Hospital Fudan University Shanghai China
出 版 物:《International Journal of Clinical Medicine》 (临床医学国际期刊(英文))
年 卷 期:2013年第4卷第7期
页 面:321-324页
学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题:Creutzfeldt-Jakob Disease Visual Disturbance Heidenhain Variant Diffusion Weighted Imaging
摘 要:Creutzfeldt-Jakob disease (CJD) is a rare but fatal neurodegenerative prion disease. Classic CJD comprises a clinical triad of rapidly progressive dementia, myoclonus, and EEG abnormality. At initial presentation, this classic triad is present only in a minority of cases. Visual impairment is one of the predominant manifestations in the course of CJD, especially in Heidenhain variant phenotype. We reported a case presenting with progressive blurred vision, along with other neurological symptoms, who diagnosed as sporadic CJD with cortical blindness in China.