Potential of <i>Syzygium aromaticum</i>(Clove) Leaf Extract on Immune Proliferation Response in Balb/c Mice Infected with <i>Salmonella typhimurium</i>
Potential of <i>Syzygium aromaticum</i>(Clove) Leaf Extract on Immune Proliferation Response in Balb/c Mice Infected with <i>Salmonella typhimurium</i>作者机构：Department of Biology Universitas Pattimura Kota Ambon Indonesia Department of Biology Universitas Gadjah Mada Yogyakarta Indonesia Department of Midwifery Poltekkes Kemenkes Surakarta Klaten Indonesia Department of Medical Diagnostics Bakti Asih College of Health Bandung Indonesia Department of Medical Laboratory Technology National College of Health Solo Indonesia Department of Veterinary Medicine Universitas Gadjah Mada Yogyakarta Indonesia
出 版 物：《Case Reports in Clinical Medicine》 (临床医学病理报告（英文）)
年 卷 期：2018年第7卷第12期
页 面：613-627页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Syzygium aromaticum Lymphocytes Lymphoblast Macrophage Salmonella typhimurium
摘 要：Background and Objective: Syzygium aromaticum is an immunomodulator with the main active compound eugenol which can stimulate the function of lymphocyte proliferation and macrophage production. Lymphocytes play an important role for body protection against infection. This study aims to analyze the effect of S. aromaticum extract to increase proliferation of lymphocytes, lymphoblasts and macrophage production in Balb/c mice infected with Salmonella typhimurium. Methodology: Mice strain Balb/c were divided into 4 groups: treatment group infected with S. typhimurium and control group (without treatment) to tested the activity of peritoneal macrophages. The treatment group was administrated by S. aromaticum leaf extract (15 mg, 75 mg, 150 mg/kgbw) for 12 days. Results: S. aromaticum leaf extract increased the proliferation activity (p Conclusion: Administration of S. aromaticum leaf extract increased the proliferation activity of lymphocytes, lymphoblasts and ROI secretion of macrophagesin Balb/c mice infected with S. typhimurium.
维普期刊数据库