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A General Model for Hepatitis B Disease with Age-Dependent Susceptibility and Transmission Probabilities

A General Model for Hepatitis B Disease with Age-Dependent Susceptibility and Transmission Probabilities

作     者:Danga Duplex Elvis Houpa Tagne Eric Miamdjo Tchaptchie Yannick Kouakep 

作者机构:Department of Mathematics and Computer Science Ngaoundéré University Ngaoundere Cameroon 

出 版 物:《Applied Mathematics》 (应用数学(英文))

年 卷 期:2014年第5卷第4期

页      面:707-722页

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主  题:A General Model for Hepatitis B Disease with Age-Dependent Susceptibility and Transmission Probabilities 

摘      要:A SEI model for hepatitis B is constructed where the susceptibility and other crucial transmission probabilities depend on the chronological age and the basic reproduction rate R0 is derived. Under suitable (biological and mathematical) assumptions in a closed population, results of Houpa D. D. E. et al. [1] are extended from constant case of p and q to age-dependent case: the disease-free equilibrium is globally asymptotically stable (GAS) if R0 . On the other hand, R0 1 induces that endemic equilibrium is GAS and the system is uniformly persistent.

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