Ozone Therapy: A Critical Physiological and Diverse Clinical Evaluation with Regard to Immune Modulation, Anti-Infectious Properties, Anti-Cancer Potential, and Impact on Anti-Oxidant Enzymes

作     者：Aaron J. Smith John Oertle Dan Warren Dino Prato 

作者机构：Envita Medical Center Scottsdale USA 

出 版 物：《Open Journal of Molecular and Integrative Physiology》 (分子和综合生理学期刊（英文）)

年 卷 期：2015年第5卷第3期

页      面：37-48页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Ozone Autohemotherapy Cancer Oxidant Lumbar Diabetes Mellitus Lung Disease Metabolome Dentistry Bacterial Infection Viral Infection 

摘      要：Ozone therapy has been marred by conventional science for years due to many flawed experimental designs or small sample sizes of the population in which it intends to study. For this reason, many physicians have dismissed ozone therapy and limited funds have been delegated to furthering the knowledge of its therapeutic effects. However, there is evidence that suggests that ozone does have various therapeutic effects that range from disinfection of pathogens, anticancer properties, and treatment of back ailments. In this paper, we have collected the more promising studies that suggest the efficacy and safety of ozone therapy primarily focusing on autohemotherapy. This paper is designed to promote awareness of ozone therapy and to show some supporting evidence of its efficacy. Clinically, ozone therapy is often used adjunctively and combined with other treatment modalities to enhance or encourage a desired mechanism of action. Since the efficacy of ozone alone is still contentious, it is important to note that ozone therapy should be used in conjunction with other various treatments with very few exceptions.