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A Modified Method for the Synthesis of Tetradentate Ligand Involving Peptide Bond

A Modified Method for the Synthesis of Tetradentate Ligand Involving Peptide Bond

作     者:Pulimamidi Rabindra Reddy Ravula Chandrashekar Hussain Shaik Battu Satyanarayana 

作者机构:Department of Chemistry Osmania University Hyderabad India 

出 版 物:《International Journal of Organic Chemistry》 (有机化学国际期刊(英文))

年 卷 期:2014年第4卷第2期

页      面:122-134页

学科分类:07[理学] 0703[理学-化学] 

主  题:Amide Bond Formation Tetradentate Ligand Peptide Bond Coupling Reagent 

摘      要:In view of the importance of picolinic acid (Pa) in preventing cell growth and arresting cell cycle, attempts were made to design, synthesize and characterize two new Pa based tetradentate ligands (DPPTR and DPPTY) with a modified procedure. The procedure reported here avoids by-products and provides better yield and purity.

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