A Microarray Analysis of Parkinson’s Disease: New Clues and Evaluation
A Microarray Analysis of Parkinson’s Disease: New Clues and Evaluation作者机构:Department of Neurology Fu Xing Hospital Capital Medical University Beijing China Department of Physiology Key Laboratory for Neurodegenerative Disorders of the Ministry of Education Captal Medical University Beijing China Department of Neurology Stanford University Stanford USA
出 版 物:《Journal of Biosciences and Medicines》 (生物科学与医学(英文))
年 卷 期:2015年第3卷第9期
页 面:55-60页
学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题:Parkinson’s Disease 6-OHDA Microarray Discrete Genes Cortex Striatum
摘 要:Parkinson’s disease (PD) is complex and most likely results from an unknown combination of genetic and environmental factors. Here, we defined discrete genes (DGs) in a microarray analysis and found that the percentage of DGs versus all analyzable genes correlated with PD progression. Furthermore, this new parameter was also easily used to evaluate the therapeutic effect of high- frequency electro-acupuncture (EA), thus improving symptoms of PD model rats.