Scleroderma and HIV Infection: A Case Report with Literature Review

作     者：I. A. Dembélé N. R. Nyanke D. Traore A. K. Souckho D. Sy M. Cissoko A. Sanogo B. B. Sangaré O. A. Cisse K. Dao K. T. Tighankpa M. Malle M. Togo A. Keita A. Traore M. Saliou Y. Fofana D. Sangaré N. Tolo N. Doumbia A. Doumbia B. B. Berthé B. D. Camara S. A. Coulibaly N. Sawadogo M. Dembélé A. K. Traore H. A. Traore 

作者机构：Internal Medicine Department Point G Teaching Hospital Bamako Mali Department of Internal Medicine Kaya Regional Hospital Kaya Burkina Faso 

出 版 物：《Open Journal of Internal Medicine》 (内科学期刊（英文）)

年 卷 期：2018年第8卷第4期

页      面：255-260页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Scleroderma HIV Internal Medicine 

摘      要：Introduction: Acquired immunodeficiency syndrome (AIDS) linked to HIV infection is accompanied by auto-immune phenomena. Autoimmune diseases can develop in people living with HIV, most in a context of good immunological control (vasculitis, anti-phospholipid syndrome). Since the advent of antiretroviral therapy, an increasing number of autoimmune connective tissue diseases such as systemic lupus erythematosus, dermatomyositis, and syndromes of Sj?gren and scleroderma have been reported. Purpose: To describe this association’s not very common scleroderma and HIV infection. Observation: We report the case of a 56-year-old lady admitted into the service for functional impotence that would have been evolving for a week. Prior to her hospitalization, she presented edemas of the lower limbs associated with anesthesia of the lower limbs for 5 months. The painting is accompanied by a productive cough and an intermittent fever. At the physical examination a weight loss (BMI = 13.74 Kg/m2), fever (38.7°C): Oral candidiasis, lower lip ulceration, perlicking, undernutrition folds, sclerodactyly and homogeneous hepatomegaly was noted. The diagnosis of immunosuppression to HIV Stage 3 with TB co-morbidity and positive hepatitis B Serology was retained while diffuse Scleroderma was selected from the ACR/EULAR criteria of 2012 with a score of 10 (sclerodactyly = 4 point;Raynaud’s phenomenon = 3 point and Ac Anti Scl 70 positive = 3 point). Conclusion: These associations of chronic pathology must be described to improve the future treatment of our patients.