Bioresponsive nanogated ensemble based on structure-switchable aptamer directed assembly and disassembly of gold nanoparticles from mesoporous silica supports
Bioresponsive nanogated ensemble based on structure-switchable aptamer directed assembly and disassembly of gold nanoparticles from mesoporous silica supports作者机构：Inner Mongolia Power Research Institute
出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)
年 卷 期：2019年第30卷第3期
页 面：779-782页
核心收录：
基 金：supported by the Inner Mongolia Power(Group) Co. Ltd. Technology Project (No. 2016-20)
主 题：Mesoporous silica DNA aptamer Controlled release Bioresponsive Nanoparticle assembly
摘 要：By taking advantage of recent advances in aptamer biology and nanotechnology, we developed a general approach for the design and fabrication of bioresponsive controlled delivery systems. It utilized the structure-switchable aptamer directed assembly and disassembly of gold nanoparticles from mesoporous silica supports, which enables the control of cargo release from the inside of the mesoporous nanoparticles specifically in the presence of target molecule.
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