Advance in Studies on Chemical Constituents, Pharmacology and Quality Control of Aquilaria sinensis

作     者：Han-Wen YUAN Jian-Ping ZHAO Yong-Bei LIU Yi-Xing QIU Qing-Ling XIE Ming-Jiao LI Ikhlas A.KHAN Wei WANG 袁汉文;赵建平;刘永蓓;邱伊星;谢青玲;李明姣;Ikhlas A. KHANa;王炜

作者机构：National Center for Natural Products ResearchResearch Institute of Pharmaceutical SciencesUniversity of MississippiMississippi 38677United States TCM and Ethnomedicine Innovation&Development International LaboratoryInnovative Drug Research InstituteSchool of PharmacyHunan University of Chinese MedicineChangshaHunan 410208Ch 

出 版 物：《Digital Chinese Medicine》 (数字中医药（英文）)

年 卷 期：2018年第1卷第4期

页      面：316-330页

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

基　　金：support from the Administration of Traditional Chinese Medicine of Hunan Province(201673) Hunan Province Universities 2011 Collaborative Innovation Center of Protection and Utilization of Hu-xiang Chinese Medicine Resources(HXZY-2015-005 and HXZY-2015-012) the State Key Subject of TCM Diagnostics in Hunan University of Chinese Medicine(2015ZYZD06) Hunan Provincial Key Laboratory of Dong Medicine(2015TP1020-02) 

主　　题：Aquilaria sinensis Thymelaeaceae Phytochemistry Pharmacological activity Quality control 

摘      要：Aquilaria sinensis(Thymelaeaceae)is widely cultivated in southern China for its significant medicinal *** resinous wood,the most used part of the plant as traditional Chinese medicine(TCM),locally called“Chen Xiang(沉香)or Chinese agarwood,has been traditionally used for the treatment of circulatory disorders,abdominal pain,vomiting,and *** date,over 249 compounds have been isolated and identified from this plant.A range of bioactivities,including α-glucosidase inhibitory effects,anti-inflammatory,cytotoxicity,neuroprotective,anti-neuroinflammatory,antimicrobial and acetylcholinesterase inhibitory effects,along with some of the pharmacological mechanisms have been reported for the pure compounds or extracts of Aquilaria *** the purpose of quality control and clinical safety of drug usage,modern analytical instruments and chemical analysis methods have been applied for analyses of Aquilaria *** order to comprehensively understand the medicinal application and to fully utilize the plant,a literature search on the herb based on databases including SciFinder,Web of Science,Pubmed,Google Scholar and others was performed and the information regarding to the phytochemistry investigations,pharmacological studies and quality control was summarized in this paper.