Antioxidant and anti-glycation activities correlates with phenolic composition of tropical medicinal herbs

作     者：JS Ramkissoon MF Mahomoodally N Ahmed AH Subratty 

作者机构：Department of Health SciencesFaculty of ScienceUniversity of MauritiusReduitMauritius School of Healthcare ScienceManchester Metropolitan UniversityManchesterUnited Kingdom Department of Health SciencesFaculty of ScienceUniversity of Mauritius.ReduitMauritius 

出 版 物：《Asian Pacific Journal of Tropical Medicine》 (亚太热带医药杂志（英文版）)

年 卷 期：2013年第6卷第7期

页      面：561-569页

核心收录：

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

基　　金：the University of Mauritius and the Tertiary Education Commission Mauritius for financial support 

主　　题：Food plants Anti-glycation AGEs Antioxidants TPC DPPH FRAP 

摘      要：To determine the contribution of total phenolic content(TPC) in glycation inhibitory activity of common tropical medicinal food and spices with potential antioxidative properties. Methods:In vitro glucose-bovine serum albumin(BSA) assay was *** extracts of ten common household condiments/herbs(Allium *** *** rulgaris, Petroselinum crispum,Murraya koenigii Spreng,Mentha piperita L.,Curcuma longa L.,Allium cepa L.,Allium fistulosum and Coriandrum sativum L.) were evaluated for antinxidative activity by 2,2-diphenyl-2-picrylhydrazyl(DPPH),and ferric reducing antioxidant power(FRAP) and the *** and tannins content were ***:Findings showed good correlation between TPC/DPPH(r= 0.8).TPC/FRAP(r= 0.8).TPC/Anti-glycation(r=0.9).DPPH/Anti-glycation (r= 0.6),FRAP/Anti-glycation(r = 0.9),Flavonoid/Anti-glycation(r=0.7) and Tannina/Antiglycation (r = 0.8) and relatively fair correlation for TPC/Flavonoids(r = 0.5) and TPC/Tannina(r = 0.5).Results imply that these plants are potential sources of natural antioxidants which have free radical scavenging activity and might be used for reducing oxidative ***:The positive glycation inhibitory and antioxidative activities of these tropical herbs suggest a possible role in targeting ageing,diabetic complications and oxidative stress related diseases.