Bi-directional Selection in Upland Rice Leads to Its Adaptive Differentiation from Lowland Rice in Drought Resistance and Productivity

作     者：Hui Xia Zhi Luo Jie Xiong Xiaosong Ma Qiaojun Lou Haibin Wei Jie Qiu Hua Yang Guolan Liu Longjiang Fan Liang Chen Lijun Luo 

作者机构：Shanghai Agrobiological Gene Center Shanghai China College of Plant Sciences & Tech no logy Huazho ng Agricultural University Wuhan China lnstitute of Crop Science & Institute of Bioinformatics College of Agriculture and Biotechnology Zhejiang University Hangzhou China These authors contributed equally to this article. 

出 版 物：《Molecular Plant》 (分子植物（英文版）)

年 卷 期：2019年第12卷第2期

页      面：170-184页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 09[农学] 

基　　金：the National Key R&D Programe of China (grant no. 2017YFD0300100) Shanghai Agriculture Applied Technology Development Program, China (grant no. G2016060107) Shanghai Natural Science Foundation (17ZR1425500) National High-Tech Research and Development Program of China (863 Plan (grant no.2014AA10A603) Shan ghai Agriculture Applied Tech no logy Developme nt Program, China (grant no. 2017-02-08-00-08-F00071) National Natural Science Foundation of China (grant no. 31501270) Shared Platform of Crop Germplasm Resources in Shanghai (18DZ2293700) 

主　　题：drought resistance upland rice ecological adaptation ecotype trade-off domestication 

摘      要：Drought resistance is required in rice breeding to address the challenge of frequent droughts . However, the evolutionary mechanism of rice drought resistance is not fully understood. We investigated the genetic differentiation between upland and lowland rice domesticated in agro-ecosystems with contrasting water-soil conditions using genome-wide SNPs. We estimated morphological differences among upland and lowland rice in drought resistance and productivity through common garden experiments. Upland rice had better drought resistance but poorer productivity. The negative correlations between traits of drought resistance and productivity are attributed to the underlying genetic trade-offs through tight linkages (e.g., DCA1 and OsCesA7) or pleiotropic effects (e.g., LAX1). The genetic trade-offs are comm on and greatly shape the evolutio n of drought resista nee in upland rice . In genomic regions associated with both productivity and drought resistance, signs of balancing selection were detected in upland rice, while signs of directional selection were detected in lowland rice, potentially contributing to their adaptive differentiation. Signs of balancing selection in upland rice resulted from bi-directional selection during its domestication in drought-prone upland *** genome-wide association analysis, we ide ntified several valuable quantitative trait loci associated with drought resista nee, for which highly differentiated genes should be considered candidates. Bi-directional selection breaking tight linkages by accumulating recombination events would be applicable in breeding water-saving and droughtresistance rice.