Progress in defining heterogeneity and modeling periglomerular cells in the olfactory bulb

作     者：YING Nan TIAN Jian YU SaiNan ZHOU Jing LING ShuCai XIA Ling YE XueSong 

作者机构：College of Biomedical Engineering & Instrument Science Zhejiang University Hangzhou 310027 China Key Laboratory of Biomedical Engineering Ministry of Education Zhejiang University Hangzhou 310027 China School of Basic Medical Sciences Zhejiang University Hangzhou 310027 China 

出 版 物：《Science China(Life Sciences)》 (中国科学（生命科学英文版）)

年 卷 期：2012年第55卷第7期

页      面：567-575页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 08[工学] 0905[农学-畜牧学] 09[农学] 071006[理学-神经生物学] 0836[工学-生物工程] 090501[农学-动物遗传育种与繁殖] 

基　　金：supported by the National Natural Science Foundation of China (Grant Nos. 30300083,30800248,60875078,and 81171416) the Natural Science Foundation of Zhejiang Province (Grant No.Z1080300) 

主　　题：periglomerular cell patch-clamp modeling and simulation heterogeneity 

摘      要：In recent years the evolution of olfactory bulb periglomerular cells,as well as the function of periglomerular cells in olfactory encoding,has attracted increasing *** of neural information encoding based on the analysis of simulation and modeling have given rise to electrophysiological models of periglomerular cells,which have an important role in the understanding of the biology of these *** this review we provide a brief introduction to the anatomy of the olfactory system and the cell types in the olfactory *** elaborate on the latest progress in the study of the heterogeneity of periglomerular cells based on different classification criteria,such as molecular markers,structure,ion channels and action ***,we discuss the several existing electrophysiological models of periglomerular cells,and we highlight the problems and defects of these ***,considering our present work,we propose a future direction for electrophysiological investigations of periglomerular cells and for the modeling of periglomerular cells and olfactory information encoding.