血管内皮生长因子:从血管形成到神经元保护
Vascular endothelial growth factor: from angiogenesis to neuroprotection作者机构：上海交通大学医学院瑞金医院麻醉科
出 版 物：《国际麻醉学与复苏杂志》 (International Journal of Anesthesiology and Resuscitation)
年 卷 期：2006年第27卷第6期
页 面：354-356页
学科分类：1001[医学-基础医学(可授医学、理学学位)] 10[医学]
基 金：上海交通大学医学院博士学科点建设基金资助项目(项目编号:BXJ0612)
主 题：血管内皮生长因子 神经元保护作用 血管形成 缺血性血管疾病 内皮细胞增殖 缺血性心肌病 中枢神经组织 VEGF
摘 要：Vascular endothelial growth factor(VEGF),a highly conserved heparin-binding protein,was found originally in vascular endothelial cells and showed a high potency for angiogenesis and endothelial *** can induce collateral growth in the ischemic tissue and therefore,is used in the treatment of ischemic vascular ***,Endogenous expression of VEGF mRNA and VEGF has been observed in neuronal cells,and its expression is up-regulated by *** its role on angiogenesis,recent evidence indicates that VEGF can also act directly on neurons to produce neurotrophic and neuroprotective effects.
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