Positron-emission tomography/computed tomography imaging in head and neck oncology:An update

作     者：Viet D Nguyen Bundhit Tantiwongkosi Wyatt J Weinheimer Frank R Miller 

作者机构：Department of RadiologyUniversity of TexasHealth Science Center at San Antonio Division of NeuroradiologyDepartment of Radiology and Otolaryngology Head Neck SurgeryUniversity of Texas Health Science Center at San Antonio Department of Otolaryn-gology Head Neck Surgery University of Texas Health Science Center at San Antonio 

出 版 物：《World Journal of Otorhinolaryngology》 (世界耳鼻咽喉科杂志)

年 卷 期：2016年第6卷第2期

页      面：23-32页

学科分类：1002[医学-临床医学] 100213[医学-耳鼻咽喉科学] 10[医学] 

主　　题：Positron emission tomography Staging Diagnosis Computed tomography Head and neck cancer Management of squamous cell carcinoma Carcinoma of unknown primary Second primary malignancy Surveillance Recurrence Prognosis 

摘      要：Cancers of the head and neck account for more than half a million cases worldwide annually, with a significant majority diagnosed as squamous cell carcinoma(HNSCC). Imaging studies such as contrast-enhanced computed tomography(CT), magnetic resonance imaging(MRI) and ^(18)F-2-fluoro-2-deoxy-D-glucose positron-emission tomography/computed tomography(^(18)F-FDG PET/CT) are widely used to determine the presence and extent of tumors and metastatic disease, both before and after treatment. Advances in PET/CT imaging have allowed it to emerge as a superior imaging modality compared to both CT and MRI, especially in detection of carcinoma of unknown primary, cervical lymph node metastasis, distant metastasis, residual/recurrent cancer and second primary tumors, often leading to alteration in management. PET/CT biomarker may further provide an overall assessment of tumor aggressiveness with prognostic implications. As new developments emerged leading to better understanding and use of PET/CT in head and neck oncology, the aim of this article is to review the roles of PET/CT in both pre- and post-treatment management of HNSCC and PET-derived parameters as prognostic indicators.