Improved Non-Covalent Biofunctionalization of Multi-Walled Carbon Nanotubes Using Carbohydrate Amphiphiles with a Butterfly-Like Polyaromatic Tail

作     者：Mohyeddin Assali Manuel Pernía Leal Inmaculada Fernández Pablo Romero-Gomez Rachid Baati Noureddine Khiar 

作者机构：Instituto de Investigaciones QuímicasC.S.I.C-Universidad de Sevillac/.Américo Vespucio49Isla de la CartujaSevilla 41092Spain Departamento de Química Orgánica y FarmacéuticaFacultad de FarmaciaUniversidad de SevillaSevilla 41012Spain Instituto de Ciencias de Materiales de SevillaC.S.I.C-Universidad de Sevillac/.Américo Vespucio49Isla de la CartujaSevilla 41092Spain Universitéde Strasbourg Facultéde Pharmacie CNRS/UMR 7199Laboratoire des Systèmes Chimiques Fonctionnels BP 6002474 route du Rhin67400 IllkirchFrance 

出 版 物：《Nano Research》 (纳米研究（英文版）)

年 卷 期：2010年第3卷第11期

页      面：764-778页

核心收录：

学科分类：08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 

基　　金：This work was supported by the Ministerio de Ciencia e Innovación(grant No.CTQ2010-21755-CO2-00) the Junta de Andalucía(grant Nos.P06-FQM-01852 and P07-FQM-2774) the Centre National de la Recherche Scientifique(France)and the Consejo Superior de Investigaciones Científicas(Egide Picasso 09543XA and Projets Internationaux de Cooperation Scientifiques Program 2008-2010) 

主　　题：Carbon nanotubes non-covalent functionalization tetrabenzo[a c g i]fluorene carbohydrates click chemistry biocompatible system 

摘      要：We have developed an efficient strategy for the non-covalent functionalization of multi-walled carbon nanotubes(MWCNTs)which allows a biomimetic presentation of carbohydrates on their surface byπ-πstacking *** strategy is based on the use of sugar-based amphiphiles functionalized with tetrabenzo[a,c,g,i]fluorene(Tbf),a polyaromatic compound with a topology that resembles a butterfly with open *** new carbohydrate-tethered Tbf amphiphiles have been synthesized in a straightforward manner using click *** reported method has been developed in order to improve the rather low ability of pyrene-based systems to exfoliate MWCNTs in *** means of thermogravimetric analysis(TGA),ultraviolet(UV),infrared(IR),and fluorescence spectroscopies the interaction between MWCNTs and the Tbf group has been found to be stronger than those involving pyrene-based amphiphilic *** resulting aggregates with a multivalent sugar exposition on their surface are able to engage in specific ligand-lectin interactions similar to glycoconjugates on a cell membrane.