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Antiparasitic Sesquiterpenes from the Cameroonian Spice Scleria striatinux and Preliminary In Vitro and In Silico DMPK Assessment

作     者:Kennedy D.Nyongbela Fidele Ntie-Kang Thomas R.Hoye Simon M.N.Efange 

作者机构:Pharmacochemistry Research GroupDepartment of ChemistryUniversity of BueaP.O.Box 63BueaCameroon Department of ChemistryUniversity of Minnesota207 Pleasant StreetSEMinneapolisMNUSA Chemical and Bioactivity Information CentreDepartment of ChemistryUniversity of BueaP.O.Box 63BueaCameroon 

出 版 物:《Natural Products and Bioprospecting》 (应用天然产物(英文))

年 卷 期:2017年第7卷第3期

页      面:235-247页

学科分类:0710[理学-生物学] 0832[工学-食品科学与工程(可授工学、农学学位)] 1007[医学-药学(可授医学、理学学位)] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 0703[理学-化学] 0901[农学-作物学] 0902[农学-园艺学] 10[医学] 

基  金:the International Cooperative Biodiversity Groups(ICBG),a program of the Fogarty International Centre of the National Institutes of Health(NIH),USA through grant(no TW00327)awarded to Professor S.M.N.Efange and Medicines for Malaria Venture(MMV) Geneva,Switzerland.The US Fulbright Council for International Exchange of Scholars(CIES)is acknowledged for grant to Kennedy D.Nyongbela to carry-out research at the University of Minnesota 

主  题:Sesquiterpenes Pharmacokinetics Drug metabolism Scleria striatinux 

摘      要:We are grateful for financial support from the International Cooperative Biodiversity Groups(ICBG),a program of the Fogarty International Centre of the National Institutes of Health(NIH),USA through grant(no TW00327)awarded to Professor *** and Medicines for Malaria Venture(MMV),Geneva,*** US Fulbright Council for International Exchange of Scholars(CIES)is acknowledged for grant to Kennedy *** to carry-out research at the University of *** wish to thank *** and *** from the Centre for Drug Candidate Optimisation(CDCO),Monash University for the DMPK *** Ntie-Kang is currently a Georg Forster fellow of the Alexander von Humboldt Foundation,*** are equally grateful to Schro¨dinger *** the academic license to use the QikProp software.

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