Small-volume solution current-time behavior study for application in reverse iontophoresis-based non-invasive blood glucose monitoring

作     者：CHANG LingQian LIU ChunXiu HE YinZeng XIAO HongHui CAI XinXia 

作者机构：State Key Laboratory of Transducer Technology Institute of Electronics Chinese Academy of Sciences Beijing 100190 China Graduate University of Chinese Academy of Sciences Beijing 100190 China 

出 版 物：《Science China Chemistry》 (中国科学（化学英文版）)

年 卷 期：2011年第54卷第1期

页      面：223-230页

核心收录：

学科分类：082304[工学-载运工具运用工程] 0905[农学-畜牧学] 08[工学] 09[农学] 080204[工学-车辆工程] 0802[工学-机械工程] 090501[农学-动物遗传育种与繁殖] 0823[工学-交通运输工程] 

基　　金：sponsored by Hi-Tech R. & D. Program of China (2007AA042105 & 2007AA04Z326) CAS Innovative Program (KGCX2-YU-916) 

主　　题：non-invasive detection current.time behavior small-volume solution mass transfer semi-infinite diffusion mathematic model 

摘      要：The reverse iontophoresis-based glucose monitoring circumstance is similar to the small-volume solution in which mass diffusion controls the current response of the electrochemical *** this study,the law of mass transfer in this type of solution was analyzed and a mathematic model was established to depict the current-time behavior of the fabricated planar electrode used in the non-invasive meter designed by ourselves.A small-volume glucose solution was directly constructed on the electrode to simulate the reverse iontophoresis-based sensing *** correctness of the model was demonstrated by *** assay was subsequently carried out to verify the practicality of the model in determination of blood *** results processed by the new method accurately traced the authentic value,confirming the advantage of the new method and the potential in clinical analysis.