Brainstem glioma progression in juvenile and adult rats

作     者：Liu Q Liu R Kashyap MV Agarwal R Shi X Wang CC Yang SH 

作者机构：Department of Pharmacology and Neuroscience University of North Texas Health Science Center Fort Worth Texas 76107 USA 

出 版 物：《中国神经肿瘤杂志》 (Chinese Journal of Neuro-Oncology)

年 卷 期：2009年第7卷第3期

页      面：203-203页

学科分类：12[管理学] 1204[管理学-公共管理] 120402[管理学-社会医学与卫生事业管理(可授管理学、医学学位)] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：脑干胶质瘤 儿童 临床分析 治疗方法 病症 

摘      要：OBJECT: Brainstem gliomas are common in children and have the worst prognosis of any brain tumor in this age group. On the other hand, brainstem gliomas are rare in adults, and the authors of some clinical studies have suggested that this lesion behaves dif ferently in adults than in children. In the present study, the authors test an orthotopic C6 brainstem glioma model in juvenile and adult rats, and investigate the biological behavior of this lesion in the 2 age groups. METHODS: The C6 glioma cells were stereotacti eally implanted into the pons of juvenile or adult male rats. Neurological presentation and survival time were recorded.