Leptomeningeal metastases originated from esophagogastric junction/gastric cancer:A brief report of two cases

作     者：Panteleimon Kountourakis Demetris Papamichael Haris Haralambous Michael Michael Georgios Nakos Sylvia Lazaridou Eleni Fotiou Vassilios Vassiliou Demetrios Andreopoulos 

作者机构：Department of Medical OncologyBOC Oncology Centre Department of RadiologyBOC Oncology Centre Department of CytologyGeneral Hospital of Nicosia Department of PathologyGeneral Hospital of Nicosia Department of Radiation OncologyBOC Oncology Centre 

出 版 物：《World Journal of Gastrointestinal Oncology》 (世界胃肠肿瘤学杂志（英文版）（电子版）)

年 卷 期：2018年第10卷第1期

页      面：56-61页

核心收录：

学科分类：1002[医学-临床医学] 10[医学] 

主　　题：Esophagogastric junction cancer Gastric cancer Leptomeningeal carcinomatosis Prognosis Investigation Therapy 

摘      要：Leptomeningeal carcinomatosis is a very rare manifestation in patients diagnosed with esophagogastric junction and gastric cancer. Its prognosis is ominous and therapy outcomes are disappointing. Herein, we present two patients; one initially diagnosed with gastric cancer and leptomeningeal carcinomatosis but no other evidence of metastatic disease and the other one initially diagnosed with esophagogastric junction cancer, who recurred solitary with leptomeningeal seedings several years after the initial diagnosis and treatment. Furthermore, a thorough and short review of the literature is carried out.