Reversibility of diabetes mellitus: Narrative review of the evidence
Reversibility of diabetes mellitus: Narrative review of the evidence作者机构:Health Services and Outcomes Research National Healthcare Group
出 版 物:《World Journal of Diabetes》 (世界糖尿病杂志(英文版)(电子版))
年 卷 期:2018年第9卷第7期
页 面:127-131页
核心收录:
主 题:Diabetes Reversibility Remission Bariatric surgery Obesity
摘 要:The global disease burden of diabetes mellitus is high. It is well-established that prediabetes is reversible but it is unclear whether diabetes is reversible once it has been diagnosed. The objective of this narrative review is to review the evidence of reversibility of diabetes me-llitus and stimulate interest in prolonged remission as a treatment target. The current evidence for bariatric surgery is stronger than intensive medical management and the evidence is stronger for type 2 diabetes pa-tients compared with type 1 diabetes patients. It is also unclear whether non obese diabetes patients would benefit from such interventions and the duration of diabetes before diabetes become irreversible. Further research is needed in this area especially with regards to the subgroup of diabetes patient who will benefit from these interventions and the long term safety and efficacy remains unknown especially with intensive me-dical management.