Gastro-entero-pancreatic neuroendocrine tumors:Is now time for a new approach?

作     者：Rossana Berardi Mariangela Torniai Agnese Savini Silvia Rinaldi Stefano Cascinu 

作者机构：Department of Medical OncologyUniversità Politecnica delle Marche 

出 版 物：《World Journal of Clinical Oncology》 (世界临床肿瘤学杂志（英文版）)

年 卷 期：2016年第7卷第2期

页      面：131-134页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：18F-fluorodeoxyglucose positron emission tomography/computed tomography Gastro-enteropancreatic neuroendocrine tumor 68Ga-DOTATATE positron emission tomography/computed tomography Diagnosis Imaging 

摘      要：Gastro-entero-pancreatic tumors(GEP-NETs) are rare neoplasms often characterized by an overexpression of somatostatin ***,radiolabeled somatostatin analogues have showed an increasing relevance both in diagnosis and treatment,especially in low-and intermediate-differentiated *** evidences have led to a growing development of new functional imaging techniques as 68 Ga-DOTATATE positron emission tomography/computed tomography(PET/CT) proved useful in the management of these *** these tumors have a heterogeneous behavior also modifying their aggressiveness through *** sometimes 18 F-fluorodeoxyglucose PET/CT appears to be more appropriate to obtain a better assessment of the *** to these considerations,the combination of different functional imaging techniques should be considered in the management of GEP-NETs patients allowing clinicians to choose the tailored therapeutic approach among available options.