Antibiotic sensitivity pattern of bacterial pathogens in the intensive care unit of Fatmawati Hospital,Indonesia

作     者：Maksum Radji Siti Fauziah Nurgani Aribinuko 

作者机构：Laboratory of Microbiology and BiotechnologyDepartment of PharmacyFaculty of Mathematics and ScienceUniversity of Indonesia Department of Intensive Care UnitFatmawati Hospital 

出 版 物：《Asian Pacific Journal of Tropical Biomedicine》 (亚太热带生物医学杂志（英文版）)

年 卷 期：2011年第1卷第1期

页      面：39-42页

学科分类：0710[理学-生物学] 0831[工学-生物医学工程（可授工学、理学、医学学位）] 1010[医学-医学技术（可授医学、理学学位）] 10[医学] 

主　　题：Antibiotic susceptibility Intensive care unit Bacterial Resistance Bacterial pathogen Sensitivity pattern Antimicrobial Resistance Pseudomonas aeruginosa Klebsiella pneumoniae Isolate Specimen 

摘      要：Objective:To evaluate the sensitivity pattern of bacterial pathogens in the intensive care unit(ICU) of a tertiary care of Falmawati Hospital Jakarta ***:A cross sectional retrospective study of bacterial pathogen was carried out on a total of 722 patients that were admitted to the ICU of Fatmawati Hospital Jakarta Indonesia during January 2009 to March 2010. All bacteria were identified by standard microbiologic methods,and(heir antibiotic susceptibility testing was performed using disk diffusion ***:Specimens were collected from 385 patients who were given antimicrobial treatment,of which 249(64.68%) were cultured positive and 136(35.32%) were *** most predominant isolate was Pseudomonas aeruginosa(***)(26.5%) followed by Klebsiella pneumoniae(***)(15.3%) and Staphylococcus epidermidis(14.9%).*** isolates showed high rate of resistance to cephalexin(95.3%),cefotaxime(64.1%),and ceftriaxone(60.9%).Amikacin was the most effective(84.4%) antibiotic against *** followed by imipenem(81.2%),and meropenem(75.0%).*** showed resistance to cephalexin(86.5%),ceftriaxone(75.7%),ceftazidime(73.0%),cefpirome(73.0%) and cefotaxime(67.9%),***:Most bacteria isolated from ICU of Fatmawati Hospital Jakarta Indonesia were resistant to the third generation of cephalosporins,and quinolone *** surveillance of antibiotic susceptibility pallerns is very important for setting orders to guide the clinician in choosing empirical or directed therapy of infected patients.