A role of IL-25,a sibling of IL-17,in triggering psoriatic skin inflammation
A role of IL-25, a sibling of IL-17, in triggering psoriatic skin inflammation作者机构:Department of Biochemistry and Molecular Cell BiologyShanghai Key Laboratory for Tumor Microenvironment and InflammationKey Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of EducationShanghai Jiao Tong University School of MedicineShanghai 200025China Shanghai Institute of ImmunologyShanghai Jiao Tong University School of MedicineChinaDepartment of Immunology and MicrobiologyShanghai Jiao Tong University School of MedicineShanghai 200025China
出 版 物:《Science China(Life Sciences)》 (中国科学(生命科学英文版))
年 卷 期:2018年第61卷第11期
页 面:1437-1438页
核心收录:
学科分类:1002[医学-临床医学] 100206[医学-皮肤病与性病学] 10[医学]
摘 要:Interleukin 25(IL-25)expressed in epithelial cells,basophils,eosinophils,mast cells and tuft cells is a member of the IL-17 cytokine *** and colleagues newly found that IL-25 expressed in keratinocytes under pathological conditions may play a critical role in psoriatic skin inflammation and autoimmunity driven by IL-17a.