Simultaneous determination of three 5-nitroimidazoles in foodstuffs by differential pulse voltammetry and chemometrics

作     者：Yi Gui Yong Nian Ni Serge Kokot 

作者机构：State Key Laboratory of Food Science and Technology Nanchang University Nanchang 330047 China Department of Chemistry Nanchang University Nanchang 330031 China Chemistry Faculty of Science and Technology Queensland University of Technology Brisbane 4001 Australia 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2011年第22卷第5期

页      面：591-594页

核心收录：

学科分类：0710[理学-生物学] 1007[医学-药学(可授医学、理学学位)] 071010[理学-生物化学与分子生物学] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 10[医学] 

主　　题：Nitroimidazoles Metronidazole Tinidazole Ornidazole Chemometrics Differential pulse voltammetry 

摘      要：The voltammetric behaviour of three 5-nitroimidazoles,metronidazole,tinidazole and ornidazole,was investigated,and a method was developed for the simultaneous determination of these compounds,based on their reduction at a hanging mercury drop electrode（HMDE） in pH 8.95 buffer with differential pulse voltammetric（DPV） *** defined voltammetric waves with peak potentials of -692,-640 and -652 mV were observed for these compounds,*** is difficult to determine them individually from their mixtures without preseparation,for their voltammetric peaks overlapped seriously,so the chemometrics were used to resolve the overlapped voltammogram and quantify the *** proposed method was successfully applied to the determination of three 5-nitroimidazoles in milk and honey samples.