From control to eradication of malaria:the end of being stuck in second gear?

作     者：Khadjavi Amina Giribaldi Giuliana Prato Mauro 

作者机构：Department of GeneticsBiology and BiochemistryUniversity of Torino Medical School10126TorinoItaly 

出 版 物：《Asian Pacific Journal of Tropical Medicine》 (亚太热带医药杂志（英文版）)

年 卷 期：2010年第3卷第5期

页      面：412-420页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：supported by the Compagnia di San Paolo-IMI grants to MP in the context of the Italian Malaria Network 

主　　题：Malaria Plasmodium falciparum Anopheles mosquito Antimalarial drugs Vaccine Vector control Hemozoin Matrix metalloproteinases 

摘      要：More than 2 billion people are at risk of malaria,which primarily affects poor populations in tropical and subtropical areas,including Southern *** malaria incidence has been reduced strongly in some parts of endemic regions by combinations of interventions,including artemisinin-based therapies and insecticide-treated bed nets,a new goal has been established recently by charity foundations which support research on malaria:the worldwide eradication of the *** away with control approaches which have been applied for the last 50 years and more focus on elimination objectives will deeply change priorities in the area of malaria treatment,chemoprevention,vector control,vaccine research and health system *** this review,actual knowledge on pathogenesis and pharmacology is discussed,and new drugs, vaccines and insecticides are described.