GIGANTEA and EARLY FLOWERING 4 in Arabidopsis Exhibit Differential Phase-Specific Genetic Influences over a Diurnal Cycle

作     者：Yumi Kim Miji Yeom Hyunmin Kim Junhyun Lim Hee Jung Koo Daehee Hwang David Somers Hong Gil Nam 

作者机构：Division of Molecular and Life Sciences POSTECH Hyojadong Pohang Kyungbuk 790-784 Republic of Korea School of Interdisciplinary Bioscience and Bioengineering POSTECH Hyojadong Pohang Kyungbuk 790-784 Republic of Korea Department of Chemical Engineering POSTECH Hyojadong Pohang Kyungbuk 790-784 Republic of Korea Integrative Biosciences and Biotechnology POSTECH Hyojadong Pohang Kyungbuk 790-784 Republic of Korea Department of Molecular Genetics The Ohio State University 244B Rightmire Hall 1060 Carmack Road Columbus OH 43210 USA National Core Research Center for Systems Bio-Dynamics POSTECH Hyojadong Pohang Kyungbuk 790-784 Republic of Korea 

出 版 物：《Molecular Plant》 (分子植物（英文版）)

年 卷 期：2012年第5卷第3期

页      面：678-687页

核心收录：

学科分类：0710[理学-生物学] 090801[农学-水产养殖] 0908[农学-水产] 07[理学] 09[农学] 071007[理学-遗传学] 0901[农学-作物学] 0902[农学-园艺学] 090102[农学-作物遗传育种] 

基　　金：Korea government (MEST): the National Researcher Support Program National Core Research Center World Class University Program 美国国立卫生研究院(NIH)项目 Supported by grants from the National Research Foundation of Korea (NRF) funded 

主　　题：microarray LHY endogenous clock GI ELF4 

摘      要：The endogenous circadian clock regulates many physiological processes related to plant survival and adapt- ability. GIGANTEA （GI）, a clock-associated protein, contributes to the maintenance of circadian period length and ampli- tude, and also regulates flowering time and hypocotyl growth in response to day length. Similarly, EARLY FLOWERING 4 （ELF4）, another clock regulator, also contributes to these processes. However, little is known about either the genetic or molecular interactions between GI and ELF4 in Arabidopsis. In this study, we investigated the genetic interactions between GI and ELF4 in the regulation of circadian clock-controlled outputs. Our mutant analysis shows that GI is epistatic to ELF4 in flowering time determination, while ELF4 is epistatic to GI in hypocotyl growth regulation. Moreover, GI and ELF4 have a synergistic or additive effect on endogenous clock regulation. Gene expression profiling of gi, elf4, and gi elf4 mutants further established that GI and ELF4 have differentially dominant influences on circadian physiological outputs at dusk and dawn, respectively. This phasing of GI and ELF4 influences provides a potential means to achieve diversity in the regulation of circadian physiological outputs, including flowering time and hypocotyl growth.